Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Streptomyces viridochromogenes |
Protein Variants | Comment | Organism |
---|---|---|
C538A | mutation of cysteine residue involved in the coordination of the [4Fe-4S] cluster, mutant shows no catalytic activity. Mutant displays a lower affinity for the IRE sequence than the wild-type aconitase as shown in gel shift assays | Streptomyces viridochromogenes |
DELTA125-129 | mutant shows lower activity compared to wild-type | Streptomyces viridochromogenes |
R763E/Q767E | mutant shows no enzymatic activity, mutant does not bind at all to IRE-like structure as shown in gel shift assays | Streptomyces viridochromogenes |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Streptomyces viridochromogenes | apo-AcnA is an RNA binding protein as shown in gel shift assays | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces viridochromogenes | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | apo-AcnA is an RNA binding protein as shown in gel shift assays | Streptomyces viridochromogenes | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AcnA | - |
Streptomyces viridochromogenes |
aconitase | - |
Streptomyces viridochromogenes |
General Information | Comment | Organism |
---|---|---|
malfunction | mutant shows severe defects in morphology and physiology, as is unable to form any aerial mycelium, spores or phosphinothricin tripeptide | Streptomyces viridochromogenes |