Literature summary for 4.2.1.3 extracted from

James, E.A.; Gygi, S.P.; Adams, M.L.; Pierce, R.H.; Fausto, N.; Aebersold, R.H.; Nelson, S.D.; Bruschi, S.A.
Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1,1,2,2-tetrafluoroethyl)-L-cysteine (2002), Biochemistry, 41, 6789-6797.

Search for more literature for 4.2.1.3

Inhibitors

Inhibitors	Comment	Organism	Structure
S(1,1,2,2)-tetrafluoroethyl-L-cysteine	inhibition of renal aconitase activity both in vivo and in vitro is a functional consequence of difluorothioamidyl-L-lysine formation by S(1,1,2,2)-tetrafluoroethyl-L-cysteine	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Rattus norvegicus	5739	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	Q9ER34	-	-
Rattus norvegicus Male Fischer 344	Q9ER34	-	-

Purification (Commentary)

Purification (Comment)	Organism
partial	Rattus norvegicus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)