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Literature summary for 4.2.1.24 extracted from

  • Guo, G.G.; Gu, M.; Etlinger, J.D.
    240-kDa proteasome inhibitor (CF-2) is identical to delta-aminolevulinic acid dehydratase (1994), J. Biol. Chem., 269, 12399-12402.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5-aminolevulinate Homo sapiens second enzyme in the heme biosynthetic pathway ?
-
?
additional information Homo sapiens the enzyme has a dual role: 1. as 5-aminolevulinate dehydatase, the second enzyme in the pathway of heme synthesis, 2. as CF-2 proteasome inhibitor ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-aminolevulinate second enzyme in the heme biosynthetic pathway Homo sapiens ?
-
?
5-aminolevulinate + 5-aminolevulinate
-
Homo sapiens porphobilinogen + 2 H2O
-
?
additional information the enzyme has a dual role: 1. as 5-aminolevulinate dehydatase, the second enzyme in the pathway of heme synthesis, 2. as CF-2 proteasome inhibitor Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
CF-2 240-kDa proteasome inhibitor Homo sapiens