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Literature summary for 4.2.1.22 extracted from
- A novel enhancing mechanism for hydrogen sulfide-producing activity of cystathionine beta-synthase (2002), J. Biol. Chem., 277, 42680-42685.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| sodium nitroprusside | enhances activity by interacting with cysteine residues, N-ethylmaleimide abolishes this effect | Rattus norvegicus |  |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| C162S | activity can be enhanced by sodium nitroprusside | Rattus norvegicus |
| C367S | activity can be enhanced by sodium nitroprusside | Rattus norvegicus |
| C476S | activity can be enhanced by sodium nitroprusside | Rattus norvegicus |
| C49S | activity can be enhanced by sodium nitroprusside | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Serine + homocysteine | - |
Rattus norvegicus | Cystathionine + H2O | - |
? | |
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Release 2023.1 (January 2023)
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