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Literature summary for 4.2.1.22 extracted from

  • Tudball, N.; Reed, M.A.
    Purification and properties of cystathionine synthase from human liver (1975), Biochem. Biophys. Res. Commun., 67, 550-555.
    View publication on PubMed
Search for more literature for 4.2.1.22

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.91
-
 L-Ser
-
 Homo sapiens
3.41
-
 homocysteine enzyme form beta Homo sapiens
3.98
-
 homocysteine enzyme form alpha Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
250000
-
 gel filtration Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Serine + homocysteine Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Storage Stability

Storage Stability Organism
-20°C, 0.1 M Tris-HCl buffer, pH 7.5, 0.1 mM pyridoxal 5'-phosphate Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Serine + homocysteine
-
 Homo sapiens Cystathionine + H2O
-
 ?
L-Serine + homocysteine
-
 Homo sapiens ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.9 8.3 enzyme form alpha Homo sapiens
8.3
-
 enzyme form beta Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate requirement Homo sapiens