Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.2.1.2 extracted from

  • Vrsalovic Presecki, A.; Zelic, B.; Vasic-Racki, D.
    Modelling of continuous L-malic acid production by porcine heart fumarase and fumarase in yeast cells (2009), Chem. Biochem. Eng. Q., 23, 519-525.
No PubMed abstract available
Search for more literature for 4.2.1.2

Activating Compound

Activating Compound Comment Organism Structure
additional information activity of permeabilized cells in hydration of fumaric acid is significantly higher than that of the non-permeabilized ones Saccharomyces sp.
additional information activity of permeabilized cells in hydration of fumaric acid is significantly higher than that of the non-permeabilized ones Saccharomyces bayanus

Application

Application Comment Organism
industry use of purified enzyme in L-malic acid production is uneconomical because whole cells are cheaper. Use of one mg of purified fumarase in continuous production of L-malic acids, corresponds to the use of enzyme in 68 g (wet weight) cells of Saccharomyces bayanus or in 120 g (wet weight) cells of baker's yeast Sus scrofa
industry use of purified enzyme in L-malic acid production is uneconomical because whole cells are cheaper. Use of one mg of purified fumarase in continuous production of L-malic acids, corresponds to the use of enzyme in 68 g (wet weight) cells of Saccharomyces bayanus or in 120 g (wet weight) cells of baker's yeast Saccharomyces sp.
industry use of purified enzyme in L-malic acid production is uneconomical because whole cells are cheaper. Use of one mg of purified fumarase in continuous production of L-malic acids, corresponds to the use of enzyme in 68 g (wet weight) cells of Saccharomyces bayanus or in 120 g (wet weight) cells of baker's yeast Saccharomyces bayanus

Inhibitors

Inhibitors Comment Organism Structure
additional information during continuous L-malic acid production, enzyme inactivation, which is not complete Saccharomyces bayanus
additional information during continuous L-malic acid production, enzyme inactivation, which is not complete Saccharomyces sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Saccharomyces bayanus 5829
-
mitochondrion
-
 Saccharomyces bayanus 5739
-

Organism

Organism UniProt Comment Textmining
Saccharomyces bayanus
-
-
-
Saccharomyces sp.
-
-
-
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fumarate + H2O
-
 Sus scrofa L-malate
-
 ?
fumarate + H2O
-
 Saccharomyces sp. L-malate
-
 ?
fumarate + H2O
-
 Saccharomyces bayanus L-malate
-
 ?

Synonyms

Synonyms Comment Organism
fumarase
-
 Sus scrofa
fumarase
-
 Saccharomyces sp.
fumarase
-
 Saccharomyces bayanus

General Information

General Information Comment Organism
physiological function fumarase in permeabilized non-growing cells used as biocatalysts for continuous production of L-malic acid Saccharomyces sp.
physiological function fumarase in permeabilized non-growing cells used as biocatalysts for continuous production of L-malic acid Saccharomyces bayanus
physiological function purified fumarase used as biocatalysts for continuous production of L-malic acid Sus scrofa