Application | Comment | Organism |
---|---|---|
medicine | fumarate immunohistochemistry may serve as a useful low-cost screening method to identify hereditary leiomyomatosis and renal cancer | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | hereditary leiomyomatosis and renal cell cancer is a hereditary cancer syndrome predisposing individuals to the development of aggressive kidney cancer. These individuals harbour a germline mutation of fumarate hydratase | Homo sapiens |
N330S | missense mutation detected in a patient with a bilateral renal cell cancer | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | hereditary leiomyomatosis and renal cell cancer is a hereditary cancer syndrome predisposing individuals to the development of aggressive kidney cancer. These individuals harbour a germline mutation of fumarate hydratase | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | hereditary leiomyomatosis and renal cell cancer is a hereditary cancer syndrome predisposing individuals to the development of aggressive kidney cancer. These individuals harbour a germline mutation of fumarate hydratase | Homo sapiens | ? | - |
? |