Crystallization (Comment) | Organism |
---|---|
trimeric form without Mn2+, hanging drop vapor diffusion method | Cryptococcus neoformans |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | metalloprotein, transition metals induce aggregation and are required for catalysis, 1 equivalent of Mn2+ per subunit induces the formation of 24-mers from the trimeric enzyme | Cryptococcus neoformans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Cryptococcus neoformans | sixth step in histidine biosynthesis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cryptococcus neoformans | P0CO22 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Cryptococcus neoformans |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate | removal of a non-acidic hydrogen atom in the dehydration reaction | Cryptococcus neoformans | 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O | - |
? | |
additional information | sixth step in histidine biosynthesis | Cryptococcus neoformans | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
multimer | 1 equivalent of Mn2+ per subunit induces the formation of 24-mers from the trimeric enzyme | Cryptococcus neoformans |
trimer | 1 equivalent of Mn2+ per subunit induces the formation of 24-mers from the trimeric enzyme | Cryptococcus neoformans |