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Literature summary for 4.2.1.133 extracted from

  • Matsuba, Y.; Nguyen, T.T.; Wiegert, K.; Falara, V.; Gonzales-Vigil, E.; Leong, B.; Schaefer, P.; Kudrna, D.; Wing, R.A.; Bolger, A.M.; Usadel, B.; Tissier, A.; Fernie, A.R.; Barry, C.S.; Pichersky, E.
    Evolution of a complex locus for terpene biosynthesis in Solanum (2013), Plant Cell, 25, 2022-2036.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene CPS2, located in a gene cluster on chromosome 8, DNA and amino acid sequence determination and analysis, phylogenetic analysis, genetic organization Solanum lycopersicum
gene CPS2, located in a gene cluster on chromosome 8, DNA and amino acid sequence determination and analysis, phylogenetic analysis, genetic organization Solanum habrochaites
gene Nt-CPS2, located in a gene cluster on chromosome 8, DNA and amino acid sequence determination and analysis, phylogenetic analysis, genetic organization Nicotiana tabacum

Organism

Organism UniProt Comment Textmining
Nicotiana tabacum G3CCC0
-
-
Solanum habrochaites
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encodes a gene CPS2 orthologue, encoding for copal-8-ol diphosphate synthase, CLS, in other Solanum sp., but which here encodes a nonfunctional protein
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Solanum lycopersicum
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encodes a gene CPS2 orthologue, encoding for copal-8-ol diphosphate synthase, CLS, in other Solanum sp., but which here encodes a nonfunctional protein
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geranylgeranyl diphosphate + H2O
-
Nicotiana tabacum (13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate i.e. copal-8-ol diphosphate ?

Synonyms

Synonyms Comment Organism
CLS
-
Nicotiana tabacum
copal-8-ol diphosphate synthase
-
Nicotiana tabacum
Nt-CPS2
-
Nicotiana tabacum

General Information

General Information Comment Organism
evolution the Solanaceae functional gene cluster evolved by duplication and divergence of TPS genes, together with alterations in substrate specificity to utilize cis-prenyl diphosphates and through the acquisition of CPT genes Solanum lycopersicum
evolution the Solanaceae functional gene cluster evolved by duplication and divergence of TPS genes, together with alterations in substrate specificity to utilize cis-prenyl diphosphates and through the acquisition of CPT genes Solanum habrochaites
evolution the Solanaceae functional gene cluster evolved by duplication and divergence of TPS genes, together with alterations in substrate specificity to utilize cis-prenyl diphosphates and through the acquisition of CPT genes Nicotiana tabacum
metabolism copal-8-ol diphosphate, which is made from the all-trans geranylgeranyl diphosphate by copal-8-ol diphosphate synthase Nt-CPS2, is the substrate for Z-abienol synthase Nicotiana tabacum