Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.2.1.130 extracted from

  • Kim, H.J.; Lee, K.Y.; Kwon, A.R.; Lee, B.J.
    Structural and functional studies of SAV0551 from Staphylococcus aureus as a chaperone and glyoxalase III (2017), Biosci. Rep., 37, BSR20171106 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.1.130

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging-drop vapor diffusion method at 20°C, the crystal structure of SAV0551 was determined at 2.6 A resolution including the additional C-terminal histidine tag Staphylococcus aureus

Protein Variants

Protein Variants Comment Organism
C190A diminished glyoxalase III activity Staphylococcus aureus
E81A diminished glyoxalase III activity Staphylococcus aureus
H191A marginal glyoxalase III activity Staphylococcus aureus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
methylglyoxal + H2O Staphylococcus aureus
-
 (R)-lactate
-
 ?
methylglyoxal + H2O Staphylococcus aureus ATCC 700699
-
 (R)-lactate
-
 ?

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus P64312
-
-
Staphylococcus aureus ATCC 700699 P64312
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methylglyoxal + H2O
-
 Staphylococcus aureus (R)-lactate
-
 ?
methylglyoxal + H2O
-
 Staphylococcus aureus ATCC 700699 (R)-lactate
-
 ?

Synonyms

Synonyms Comment Organism
glyoxalase III
-
 Staphylococcus aureus
SAV0551
-
 Staphylococcus aureus

Cofactor

Cofactor Comment Organism Structure
additional information glyoxalase III does not require any cofactors Staphylococcus aureus