BRENDA - Enzyme Database
show all sequences of 4.2.1.111

1,5-Anhydro-D-fructose: biocatalytic and chemical synthetic methods for the preparation, transformation and derivatization

Lundt, I.; Yu, S.; Carbohydr. Res. 345, 181-190 (2010)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
EDTA
50 mM of EDTA inhibits AFDH activity by 84%
Anthracobia melaloma
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Ca2+
the activity increases by around 2fold in the presence of 10 mM CaCl2
Anthracobia melaloma
Mg2+
the activity increases by around 2fold in the presence of 25 mM MgCl2
Anthracobia melaloma
Na+
the activity increases by around 2fold in the presence of 0.1 M NaCl
Anthracobia melaloma
Organism
Organism
UniProt
Commentary
Textmining
Anthracobia melaloma
-
-
-
Peziza petersii
-
-
-
Plicaria carbonaria
-
-
-
Plicaria leiocarpa
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
1,5-anhydro-D-fructose
AFDH is highly specific towards 1,5-anhydro-D-fructose
703073
Anthracobia melaloma
1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O
-
-
-
?
1,5-anhydro-D-fructose
AFDH is highly specific towards 1,5-anhydro-D-fructose
703073
Plicaria carbonaria
1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O
-
-
-
?
1,5-anhydro-D-fructose
AFDH is highly specific towards 1,5-anhydro-D-fructose
703073
Plicaria leiocarpa
1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O
-
-
-
?
1,5-anhydro-D-fructose
AFDH is highly specific towards 1,5-anhydro-D-fructose
703073
Peziza petersii
1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O
-
-
-
?
additional information
AFDH is inactive towards D-glucose, D-galactose, D-mannose, D-fructose and D-ribose
703073
Anthracobia melaloma
?
-
-
-
?
additional information
AFDH is inactive towards D-glucose, D-galactose, D-mannose, D-fructose and D-ribose
703073
Plicaria carbonaria
?
-
-
-
?
additional information
AFDH is inactive towards D-glucose, D-galactose, D-mannose, D-fructose and D-ribose
703073
Plicaria leiocarpa
?
-
-
-
?
additional information
AFDH is inactive towards D-glucose, D-galactose, D-mannose, D-fructose and D-ribose
703073
Peziza petersii
?
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
AFDH
-
Anthracobia melaloma
AFDH
-
Plicaria carbonaria
AFDH
-
Plicaria leiocarpa
AFDH
-
Peziza petersii
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.5
-
-
Anthracobia melaloma
pH Range
pH Minimum
pH Maximum
Commentary
Organism
5.9
7
-
Anthracobia melaloma
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
EDTA
50 mM of EDTA inhibits AFDH activity by 84%
Anthracobia melaloma
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Ca2+
the activity increases by around 2fold in the presence of 10 mM CaCl2
Anthracobia melaloma
Mg2+
the activity increases by around 2fold in the presence of 25 mM MgCl2
Anthracobia melaloma
Na+
the activity increases by around 2fold in the presence of 0.1 M NaCl
Anthracobia melaloma
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
1,5-anhydro-D-fructose
AFDH is highly specific towards 1,5-anhydro-D-fructose
703073
Anthracobia melaloma
1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O
-
-
-
?
1,5-anhydro-D-fructose
AFDH is highly specific towards 1,5-anhydro-D-fructose
703073
Plicaria carbonaria
1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O
-
-
-
?
1,5-anhydro-D-fructose
AFDH is highly specific towards 1,5-anhydro-D-fructose
703073
Plicaria leiocarpa
1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O
-
-
-
?
1,5-anhydro-D-fructose
AFDH is highly specific towards 1,5-anhydro-D-fructose
703073
Peziza petersii
1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O
-
-
-
?
additional information
AFDH is inactive towards D-glucose, D-galactose, D-mannose, D-fructose and D-ribose
703073
Anthracobia melaloma
?
-
-
-
?
additional information
AFDH is inactive towards D-glucose, D-galactose, D-mannose, D-fructose and D-ribose
703073
Plicaria carbonaria
?
-
-
-
?
additional information
AFDH is inactive towards D-glucose, D-galactose, D-mannose, D-fructose and D-ribose
703073
Plicaria leiocarpa
?
-
-
-
?
additional information
AFDH is inactive towards D-glucose, D-galactose, D-mannose, D-fructose and D-ribose
703073
Peziza petersii
?
-
-
-
?
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.5
-
-
Anthracobia melaloma
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
5.9
7
-
Anthracobia melaloma
Other publictions for EC 4.2.1.111
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
703073
Lundt
1,5-Anhydro-D-fructose: biocat ...
Anthracobia melaloma, Plicaria carbonaria, Plicaria leiocarpa, Peziza petersii
Carbohydr. Res.
345
181-190
2010
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1
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3
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4
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8
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4
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1
1
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1
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3
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8
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1
1
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667822
Yu
The anhydrofructose pathway an ...
Anthracobia melaloma, Plicaria carbonaria, Plicaria leiocarpa
Biochim. Biophys. Acta
1760
1314-1322
2006
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1
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3
2
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3
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4
1
6
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1
1
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1
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3
2
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4
1
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1
1
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650418
Yu
Enzymatic description of the a ...
Anthracobia melaloma
Biochim. Biophys. Acta
1672
120-129
2004
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2
1
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1
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1
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1
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2
1
6
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2
1
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1
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1
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2
1
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