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Literature summary for 4.2.1.11 extracted from

  • Pietkiewicz, J.; Bronowicka-Szyde?ko, A.; Dzierzba, K.; Danielewicz, R.; Gamian, A.
    Glycation of the muscle-specific enolase by reactive carbonyls: effect of temperature and the protection role of carnosine, pyridoxamine and phosphatidylserine (2011), Protein J., 30, 149-158.
    View publication on PubMed
Search for more literature for 4.2.1.11

Inhibitors

Inhibitors Comment Organism Structure
4-hydroxy-2-nonenal
-
 Homo sapiens
4-hydroxy-2-nonenal
-
 Sus scrofa
acrolein
-
 Homo sapiens
acrolein
-
 Sus scrofa
methylglyoxal
-
 Homo sapiens
methylglyoxal
-
 Sus scrofa
additional information the muscle-specific enolase is used as a model enzyme for inhibition analysis by acrolein, 4-hydroxy-2-nonenal, and trans-2-nonenal, incubation for 1-24 h at 25°C, 37°C, and 45°C, overview. The compounds show inhibition effectivity in the following descending order: inhibition degree of enolase activity occurred in following order: 4-hydroxy-2-nonenal, acrolein, methylglyoxal, trans-2-nonenal, overview Homo sapiens
additional information the muscle-specific enolase is used as a model enzyme for inhibition analysis by acrolein, 4-hydroxy-2-nonenal, and trans-2-nonenal, incubation for 1-24 h at 25°C, 37°C, and 45°C, overview. The compounds show inhibition effectivity in the following descending order: inhibition degree of enolase activity occurred in following order: 4-hydroxy-2-nonenal, acrolein, methylglyoxal, trans-2-nonenal, overview Sus scrofa
trans-2-nonenal
-
 Homo sapiens
trans-2-nonenal
-
 Sus scrofa

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
native enzyme from muscle by ammonium sulfate fractionation and ion exchange chromatography Homo sapiens
native enzyme from muscle by ammonium sulfate fractionation and ion exchange chromatography Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle muscle-specific enolase Homo sapiens
-
skeletal muscle muscle-specific enolase Sus scrofa
-

Synonyms

Synonyms Comment Organism
beta-enolase
-
 Homo sapiens
beta-enolase
-
 Sus scrofa
enolase
-
 Homo sapiens
enolase
-
 Sus scrofa

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
22
-
 assay at room temperature Homo sapiens
22
-
 assay at room temperature Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
 assay at Homo sapiens
6.8
-
 assay at Sus scrofa

General Information

General Information Comment Organism
additional information the human muscle-specific enolase is less susceptible to inactivation by reactive aldehydes than the pig enzyme Homo sapiens
additional information the human muscle-specific enolase is less susceptible to inactivation by reactive aldehydes than the pig enzyme Sus scrofa