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Literature summary for 4.2.1.11 extracted from

  • Butterfield, D.A.; Lange, M.L.
    Multifunctional roles of enolase in Alzheimers disease brain: beyond altered glucose metabolism (2009), J. Neurochem., 111, 915-933.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.1.11

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48000
-
 alpha-enolase Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phospho-D-glycerate
-
 Homo sapiens phosphoenolpyruvate + H2O
-
 r

Synonyms

Synonyms Comment Organism
alpha-enolase
-
 Homo sapiens
ENO1
-
 Homo sapiens
gamma-enolase
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens alpha-enolase is consistently up-regulated from mild cognitive impairment to Alzheimer's disease up

General Information

General Information Comment Organism
metabolism alpha-enolase is involved in glucose metabolism in Alzheimer's disease brain Homo sapiens
physiological function glycolytic/gluconeogenesis enzyme, eye lens tau-crystallin protein, plasminogen binding protein, c-Myc binding protein and transcription factor in tumor formationk Homo sapiens