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Literature summary for 4.2.1.11 extracted from

  • Tu, S.H.; Chang, C.C.; Chen, C.S.; Tam, K.W.; Wang, Y.J.; Lee, C.H.; Lin, H.W.; Cheng, T.C.; Huang, C.S.; Chu, J.S.; Shih, N.Y.; Chen, L.C.; Leu, S.J.; Ho, Y.S.; Wu, C.H.
    Increased expression of enolase alpha in human breast cancer confers tamoxifen resistance in human breast cancer cells (2010), Breast Cancer Res. Treat., 121, 539-553.
    View publication on PubMed

Application

Application Comment Organism
medicine changes in tumor ENO-1 levels are related to clinical 4-hydroxytamoxifen therapeutic outcome, downregulation of ENO-1 can be utilized as a pharmacological approach for overcoming 4-hydroxytamoxifen resistance in breast cancer therapy Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
AU-565 cell
-
Homo sapiens
-
breast cancer cell
-
Homo sapiens
-
BT-483 cell
-
Homo sapiens
-
HBL-100 cell
-
Homo sapiens
-
MCF-10A cell
-
Homo sapiens
-
MCF-7 cell
-
Homo sapiens
-
MDA-MB-231 cell
-
Homo sapiens
-
MDA-MB-453 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phospho-D-glycerate
-
Homo sapiens phosphoenolpyruvate
-
r

Synonyms

Synonyms Comment Organism
ENO-1
-
Homo sapiens
enolase-alpha
-
Homo sapiens