Literature summary for 4.2.1.1 extracted from

Jewell, D.A.; Tu, C.; Paranawithana, S.R.; Tanhauser, S.M.; LoGrasso, P.V.; Laipis, P.J.; Silverman, D.N.
Enhancement of the catalytic properties of human carbonic anhydrase III by site-directed mutagenesis (1991), Biochemistry, 30, 1484-1490.

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Protein Variants

Protein Variants	Comment	Organism
K64H	mutant of carbonic anhydrase III, pH-dependent behavior and enhanced CO2 hydration activity compared to the wild-type enzyme, no enhanced hydrolysis rate	Homo sapiens
R67N	mutant of carbonic anhydrase III, pH-dependent behavior and enhanced CO2 hydration activity compared to the wild-type enzyme, no enhanced hydrolysis rate	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	carbonic anhydrase III	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CO2 + H2O	among the seven known isozymes carbonic anhydrase III is the least efficient in catalytic hydration of CO2	Homo sapiens	H2CO3	-	r

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Release 2023.1 (January 2023)