Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.1.99.3 extracted from

  • Walter, D.; Boswell, M.; Volk de Garcia, S.; Walter, S.; Breitenfeldt, E.; Boswell, W.; Walter, R.
    Characterization and differential expression of CPD and 6-4 DNA photolyases in Xiphophorus species and interspecies hybrids (2014), Comp. Biochem. Physiol. C, 163, 77-85 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.99.3

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative real-time PCR enzyme expression analysis Xiphophorus maculatus
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative real-time PCR enzyme expression analysis Xiphophorus couchianus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cyclobutadipyrimidine (in DNA) Xiphophorus maculatus
-
 2 pyrimidine residues (in DNA)
-
 ?
cyclobutadipyrimidine (in DNA) Xiphophorus couchianus
-
 2 pyrimidine residues (in DNA)
-
 ?
cyclobutadipyrimidine (in DNA) Xiphophorus maculatus Jp 163 B
-
 2 pyrimidine residues (in DNA)
-
 ?

Organism

Organism UniProt Comment Textmining
Xiphophorus couchianus
-
 and F1 interspecies hybrids made by crossing these two parental lines, i.e. Xiphophorus maculatus Jp 163 B × Xiphophorus couchianus
-
Xiphophorus maculatus
-
 and F1 interspecies hybrids made by crossing these two parental lines, i.e. Xiphophorus maculatus Jp 163 B × Xiphophorus couchianus
-
Xiphophorus maculatus Jp 163 B
-
 and F1 interspecies hybrids made by crossing these two parental lines, i.e. Xiphophorus maculatus Jp 163 B × Xiphophorus couchianus
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Xiphophorus maculatus
-
brain
-
 Xiphophorus couchianus
-
eye
-
 Xiphophorus maculatus
-
eye
-
 Xiphophorus couchianus
-
gill
-
 Xiphophorus maculatus
-
gill
-
 Xiphophorus couchianus
-
heart
-
 Xiphophorus maculatus
-
heart
-
 Xiphophorus couchianus
-
liver
-
 Xiphophorus maculatus
-
liver
-
 Xiphophorus couchianus
-
additional information tissue expression pattern, overview. The F1 interspecies hybrid exhibits much higher basal transcription levels of CPD photolyase then either parental line in light responsive organs (about 30fold in skin and about 4fold in eyes). For other organs, the F1 interspecies hybrid exhibits higher basal expression of CPD photolyase than either parental line in gill and heart, while showing basal levels similar to the Xiphophorus maculatus in brain (about 2.5fold above Xiphophorus couchianus) and basal levels similar to Xiphophorus couchianus for testis and liver (9.4 and 7.7fold above Xiphophorus maculatus, respectively) Xiphophorus maculatus
-
additional information tissue expression pattern, overview. The F1 interspecies hybrid exhibits much higher basal transcription levels of CPD photolyase then either parental line in light responsive organs (about 30fold in skin and about 4fold in eyes). For other organs, the F1 interspecies hybrid exhibits higher basal expression of CPD photolyase than either parental line in gill and heart, while showing basal levels similar to the Xiphophorus maculatus in brain (about 2.5fold above Xiphophorus couchianus) and basal levels similar to Xiphophorus couchianus for testis and liver (9.4 and 7.7fold above Xiphophorus maculatus, respectively) Xiphophorus couchianus
-
skin fluorescent light induction of CPD photolyase in skin Xiphophorus maculatus
-
skin fluorescent light induction of CPD photolyase in skin Xiphophorus couchianus
-
testis testis exhibits very high basal expression values in the F1 interspecies hybrid for CPD photolyase, about 9.4fold higher than liver Xiphophorus maculatus
-
testis testis exhibits very high basal expression values in the F1 interspecies hybrid for CPD photolyase, about 9.4fold higher than liver Xiphophorus couchianus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyclobutadipyrimidine (in DNA)
-
 Xiphophorus maculatus 2 pyrimidine residues (in DNA)
-
 ?
cyclobutadipyrimidine (in DNA)
-
 Xiphophorus couchianus 2 pyrimidine residues (in DNA)
-
 ?
cyclobutadipyrimidine (in DNA)
-
 Xiphophorus maculatus Jp 163 B 2 pyrimidine residues (in DNA)
-
 ?

Synonyms

Synonyms Comment Organism
CPD photolyase
-
 Xiphophorus maculatus
CPD photolyase
-
 Xiphophorus couchianus

Expression

Organism Comment Expression
Xiphophorus maculatus photolyase gene expression patterns before and after exposure to fluorescent light in Xiphophorus maculatus, Xiphophorus couchianus, and for F1 interspecies hybrids produced from crossing these two parental lines (Xiphophorus maculatus Jp 163 B × Xiphophorus couchianus). Fluorescent light induction of CPD photolyase in skin up
Xiphophorus couchianus photolyase gene expression patterns before and after exposure to fluorescent light in Xiphophorus maculatus, Xiphophorus couchianus, and for F1 interspecies hybrids produced from crossing these two parental lines (Xiphophorus maculatus Jp 163 B × Xiphophorus couchianus). Fluorescent light induction of CPD photolyase in skin up

General Information

General Information Comment Organism
physiological function UVB-induced DNA lesions in Xiphophorus fishes are thought to primarily be repaired via light dependent CPD and 6-4PP specific photolyases, cf. EC 4.1.99.13 Xiphophorus maculatus
physiological function UVB-induced DNA lesions in Xiphophorus fishes are thought to primarily be repaired via light dependent CPD and 6-4PP specific photolyases, cf. EC 4.1.99.13 Xiphophorus couchianus