Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.1.99.3 extracted from

  • Oztuerk, N.; Kao, Y.T.; Selby, C.P.; Kavakli, I.H.; Partch, C.L.; Zhong, D.; Sancar, A.
    Purification and characterization of a type III photolyase from Caulobacter crescentus (2008), Biochemistry, 47, 10255-10261.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.99.3

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli strain UNC523 Caulobacter vibrioides

Protein Variants

Protein Variants Comment Organism
W395R the mutation compromises FAD binding of wild type enzyme without significantly affecting the overall conformation of photolyase, the mutant has essentially lost its DNA binding activity, and the residual activity that remains cannot discriminate between damaged and undamaged DNA Caulobacter vibrioides

Organism

Organism UniProt Comment Textmining
Caulobacter vibrioides
-
-
-
Caulobacter vibrioides CB15
-
-
-

Purification (Commentary)

Purification (Comment) Organism
amylose resin column chromatography Caulobacter vibrioides

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyclobutadipyrimidine in DNA
-
 Caulobacter vibrioides pyrimidine residues in DNA
-
 ?
cyclobutadipyrimidine in DNA
-
 Caulobacter vibrioides CB15 pyrimidine residues in DNA
-
 ?

Synonyms

Synonyms Comment Organism
photolyase member of the class type III photolyases Caulobacter vibrioides
PHR
-
 Caulobacter vibrioides

Cofactor

Cofactor Comment Organism Structure
5,10-methenyltetrahydrofolate
-
 Caulobacter vibrioides
FAD
-
 Caulobacter vibrioides