Cloned (Comment) | Organism |
---|---|
overexpression in Escherichia coli | Clostridium acetobutylicum |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe | iron-sulfur enzyme, 2.9 Fe per enzyme | Clostridium acetobutylicum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(5''R)-alpha-5''(6''H)-bithymine + S-adenosyl-L-methionine | Clostridium acetobutylicum | SPL repairs specifically the 5R isomer. (5''R)-alpha-5''(6''H)-bithymine is the diastereomer produced upon UV irradiation of a TpT dinucleotide | thymidylyl-(3'-5')-thymidylate + 5'-deoxyadenosine + L-methionine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clostridium acetobutylicum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(5''R)-alpha-5''(6''H)-bithymine + S-adenosyl-L-methionine | SPL repairs specifically the 5R isomer. (5''R)-alpha-5''(6''H)-bithymine is the diastereomer produced upon UV irradiation of a TpT dinucleotide | Clostridium acetobutylicum | thymidylyl-(3'-5')-thymidylate + 5'-deoxyadenosine + L-methionine | - |
? | |
(5''R)-alpha-5''(6''H)-bithymine + S-adenosyl-L-methionine | SPL repairs specifically the 5R isomer | Clostridium acetobutylicum | thymidylyl-(3'-5')-thymidylate + 5'-deoxyadenosine + L-methionine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SP lyase | - |
Clostridium acetobutylicum |
SPL | - |
Clostridium acetobutylicum |