Literature summary for 4.1.99.1 extracted from

Gogoleva, O.I.; Zakomirdina, L.N.; Demidkina, T.V.; Phillips, R.S.; Faleev, N.G.
Tryptophanase in aqueous methanol: the solvent effects and a probable mechanism of the hydrophobic control of substrate specificity (2003), Enzyme Microb. Technol., 32, 843-850.

No PubMed abstract available

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Inhibitors

Inhibitors	Comment	Organism	Structure
D,L-homophenylalanine	-	Escherichia coli
L-alanine	-	Escherichia coli
L-methionine	-	Escherichia coli
L-phenylalanine	-	Escherichia coli
L-tryptophan	-	Escherichia coli
additional information	inhibitors in aqueous methanol	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
L-tryptophan + H2O = indole + pyruvate + NH3	mechanism, solvent effects	Escherichia coli	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-oxindolyl-L-alanine + H2O	-	Escherichia coli	?	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
additional information	-	additional information	Ki-values for reaction in aqueous methanol	Escherichia coli
0.067	-	D,L-homophenylalanine	pH 7.8	Escherichia coli
0.21	-	L-tryptophan	pH 7.8	Escherichia coli
10.3	-	L-methionine	pH 7.8	Escherichia coli
14	-	L-alanine	pH 7.8	Escherichia coli
14.2	-	L-phenylalanine	pH 7.8	Escherichia coli

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Release 2023.1 (January 2023)