BRENDA - Enzyme Database show
show all sequences of 4.1.3.36

Enzymatic synthesis, characterization, and metabolism of the coenzyme A ester of o-succinylbenzoic acid, an intermediate in menaquinone (vitamin K2) biosynthesis

Heide, L.; Arendt, S.; Leistner, E.; J. Biol. Chem. 257, 7396-7400 (1982)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
additional information
little or no inhibition by dimethylamide
Escherichia coli
additional information
little or no inhibition by dimethylamide
Mycolicibacterium phlei
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
additional information
no metal ion required
Escherichia coli
additional information
no metal ion required
Mycolicibacterium phlei
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Escherichia coli
-
K-12
-
Mycolicibacterium phlei
-
-
-
Purification (Commentary)
Commentary
Organism
-
Escherichia coli
-
Mycolicibacterium phlei
Storage Stability
Storage Stability
Organism
-20°C, E. coli K-12, not less than 6 weeks
Escherichia coli
-20°C, Mycobacterium phlei, in 3-(N-morpholino)propanesulfonic acid buffer, pH 6.9, 0.2 mM DTT, 20% DMSO, not less than 6 weeks
Mycolicibacterium phlei
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
O-succinylbenzoyl-CoA
-
93962
Escherichia coli
1,4-dihydroxy-2-naphthoate + CoA
-
93962
Escherichia coli
?
O-succinylbenzoyl-CoA
-
93962
Mycolicibacterium phlei
1,4-dihydroxy-2-naphthoate + CoA
-
93962
Mycolicibacterium phlei
?
Cofactor
Cofactor
Commentary
Organism
Structure
additional information
no cofactor required
Escherichia coli
additional information
no cofactor required
Mycolicibacterium phlei
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
additional information
no cofactor required
Escherichia coli
additional information
no cofactor required
Mycolicibacterium phlei
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
additional information
little or no inhibition by dimethylamide
Escherichia coli
additional information
little or no inhibition by dimethylamide
Mycolicibacterium phlei
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
additional information
no metal ion required
Escherichia coli
additional information
no metal ion required
Mycolicibacterium phlei
Purification (Commentary) (protein specific)
Commentary
Organism
-
Escherichia coli
-
Mycolicibacterium phlei
Storage Stability (protein specific)
Storage Stability
Organism
-20°C, E. coli K-12, not less than 6 weeks
Escherichia coli
-20°C, Mycobacterium phlei, in 3-(N-morpholino)propanesulfonic acid buffer, pH 6.9, 0.2 mM DTT, 20% DMSO, not less than 6 weeks
Mycolicibacterium phlei
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
O-succinylbenzoyl-CoA
-
93962
Escherichia coli
1,4-dihydroxy-2-naphthoate + CoA
-
93962
Escherichia coli
?
O-succinylbenzoyl-CoA
-
93962
Mycolicibacterium phlei
1,4-dihydroxy-2-naphthoate + CoA
-
93962
Mycolicibacterium phlei
?
Other publictions for EC 4.1.3.36
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
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4
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4
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2
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4
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4
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3
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2
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2
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2
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2
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2
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2
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-
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-
2
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6
6
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714260
Chen
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Escherichia coli
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5893-5904
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1
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4
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1
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8
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4
4
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1
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2
8
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6
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1
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6
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6
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ACS Med. Chem. Lett.
2
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1
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3
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18
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1
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-
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18
20
3
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1
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3
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11
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1
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11
15
3
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1
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Geobacillus kaustophilus
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1
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4
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1
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1
1
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1
1
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677390
Ulaganathan
Structure of Staphylococcus au ...
Staphylococcus aureus
Acta Crystallogr. Sect. F
63
908-913
2007
-
-
1
1
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1
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4
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1
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1
1
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1
1
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663500
Johnston
Structure of naphthoate syntha ...
Mycobacterium tuberculosis
Acta Crystallogr. Sect. D
61
1199-1206
2005
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-
1
1
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5
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1
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1
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93959
Kolkmann
4-(2'-Carboxyphenyl)-4-oxobuty ...
Escherichia coli, Galium mollugo, Mycolicibacterium phlei
Z. Naturforsch. C
42
1207-1214
1987
-
-
-
-
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3
-
3
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3
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2
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6
-
3
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3
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3
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2
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6
-
3
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93961
Shaw
-
Recombinent plasmids containin ...
Escherichia coli
FEMS Microbiol. Lett.
17
63-67
1983
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1
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1
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93962
Heide
Enzymatic synthesis, character ...
Escherichia coli, Mycolicibacterium phlei
J. Biol. Chem.
257
7396-7400
1982
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2
2
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93960
Heide
Enzymatic synthesis of the coe ...
Mycolicibacterium phlei
FEBS Lett.
128
201-204
1981
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1
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1
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1
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1
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1
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2
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1
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93958
Meganathan
Menaquinone (vitamin K2) biosy ...
Mycolicibacterium phlei
J. Bacteriol.
140
92-98
1979
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2
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