Literature summary for 4.1.3.36 extracted from

Ulaganathan, V.; Agacan, M.F.; Buetow, L.; Tulloch, L.B.; Hunter, W.N.
Structure of Staphylococcus aureus1,4-dihydroxy-2-naphthoyl-CoA synthase (MenB) in complex with acetoacetyl-CoA (2007), Acta Crystallogr. Sect. F, 63, 908-913.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli strain BL21(DE3)	Staphylococcus aureus

Crystallization (Commentary)

Crystallization (Comment)	Organism
sitting drop vapour diffusion method with 0.1 M NaHEPES pH 7.5, 1.6 M ammonium sulfate, 0.2 M NaCl	Staphylococcus aureus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
185000	-	gel filtration	Staphylococcus aureus

Organism

Organism	UniProt	Comment	Textmining
Staphylococcus aureus	Q5HH38	-	-

Purification (Commentary)

Purification (Comment)	Organism
HiTrap Chelating HP column chromatography and HiTrap column chromatography	Staphylococcus aureus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
o-succinylbenzoyl-CoA	-	Staphylococcus aureus	1,4-dihydroxy-2-naphthoyl-CoA + H2O	-	?

Subunits

Subunits	Comment	Organism
hexamer	gel filtration	Staphylococcus aureus

Synonyms

Synonyms	Comment	Organism
1,4-dihydroxy-2-naphthoyl-CoA synthase	-	Staphylococcus aureus
MenB	-	Staphylococcus aureus

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Release 2023.1 (January 2023)