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Literature summary for 4.1.3.27 extracted from

  • Dubouzet, J.G.; Matsuda, F.; Ishihara, A.; Miyagawa, H.; Wakasa, K.
    Production of indole alkaloids by metabolic engineering of the tryptophan pathway in rice (2013), Plant Biotechnol. J., 11, 1103-1111.
    View publication on PubMed

Application

Application Comment Organism
biotechnology Oryza sativacalli overexpressing OASA1D:OASA1D is a system for the production of significant amounts of pharmacologically useful indole alkaloids in rice Oryza sativa
synthesis Oryza sativacalli overexpressing OASA1D:OASA1D is a system for the production of significant amounts of pharmacologically useful indole alkaloids in rice Oryza sativa

Cloned(Commentary)

Cloned (Comment) Organism
phylogenetic analysis, Agrobacterium-mediated co-overexpression of OsTDC, a putative tryptophan decarboxylase gene from rice, with OASA1D, the feedback-resistant anthranilate synthase alpha-subunit mutant in Oryza sativa calli, real-time quantitative reverse-transcription PCR expression analysis Oryza sativa

Protein Variants

Protein Variants Comment Organism
additional information tryptophan decarboxylase inactivity is a contributory factor for the accumulation of Trp in rice transgenics overexpressing the feedback-resistant anthranilate synthase alpha-subunit mutant OASA1D, high-Trp transgenic line overexpressing OASA1D line HW5 phenotype, overview. The calli expressing OsTDC and OASA1D reveal the accumulation of serotonin and serotonin-derived indole compounds (potentially pharmacoactive beta-carbolines), and of two epimers of 2-hydroxy-3-(3'-aminoethyl-5'-hydroxyindol-2'-yl)-3-indol-3'-yl-propyl beta-D-glucopyranoside not described previously. Metabolic profiles, overview Oryza sativa

Organism

Organism UniProt Comment Textmining
Oryza sativa
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Oryza sativa Nipponbare
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Synonyms

Synonyms Comment Organism
ASA
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Oryza sativa