Inhibitors | Comment | Organism | Structure |
---|---|---|---|
glyoxylate | - |
Rattus norvegicus | |
pyruvate | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.11 | - |
D-4-hydroxy-2-oxoglutarate | - |
Rattus norvegicus | |
0.22 | - |
L-4-hydroxy-2-oxoglutarate | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | no requirement | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
120000 | - |
gel filtration | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-hydroxy-2-oxoglutarate | Rattus norvegicus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
rat | - |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
8 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-Hydroxy-2-oxoglutarate | both stereoisomers | Rattus norvegicus | Pyruvate + glyoxylate | - |
? | |
4-hydroxy-2-oxoglutarate | - |
Rattus norvegicus | ? | - |
? | |
D-4-hydroxy-2-oxoglutarate | - |
Rattus norvegicus | pyruvate + glyoxylate | - |
? | |
L-4-hydroxy-2-oxoglutarate | - |
Rattus norvegicus | pyruvate + glyoxylate | - |
? | |
additional information | acts on both stereoisomers | Rattus norvegicus | ? | - |
? | |
additional information | 2-keto-3-deoxyglucarate and 2-keto-4,5-dihydroxyvalerate cleaved at slow rate | Rattus norvegicus | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
enzyme assay at | Rattus norvegicus |