Literature summary for 4.1.2.9 extracted from

Shinkawa, S.; Okano, K.; Yoshida, S.; Tanaka, T.; Ogino, C.; Fukuda, H.; Kondo, A.
Improved homo L-lactic acid fermentation from xylose by abolishment of the phosphoketolase pathway and enhancement of the pentose phosphate pathway in genetically modified xylose-assimilating Lactococcus lactis (2011), Appl. Microbiol. Biotechnol., 91, 1537-1544.

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Application

Application	Comment	Organism
synthesis	a phosphoketolase disruption mutant harboring the pXylRAB gene for catabolism of xylose lacks the phosphoketolasepathwas pathway and produces predominantly lactic acid from xylose via the pentose phosphate pathway, although its fermentation rate slightly decreases. Further introduction of the transketolase gene to disrupted phosphoketolase locus leads to restoration of the fermentation rate. As a result, the strain produces 50.1 g/l of L-lactic acid from xylose with a optical purity of 99.6% and a yield of 1.58 mol per mole xylose consumed	Lactococcus lactis

Cloned(Commentary)

Cloned (Comment)	Organism
-	Lactococcus lactis

Organism

Organism	UniProt	Comment	Textmining
Lactococcus lactis	-	-	-

General Information

General Information	Comment	Organism
physiological function	a phosphoketolase disruption mutant harboring the pXylRAB gene for catabolism of xylose lacks the phosphoketolase pathway and produces predominantly lactic acid from xylose via the pentose phosphate pathway, although its fermentation rate slightly decreases. Further introduction of the transketolase gene to disrupted phosphoketolase locus leads to restoration of the fermentation rate. As a result, the strain produces 50.1 g/l of L-lactic acid from xylose with a optical purity of 99.6% and a yield of 1.58 mol per mole xylose consumed	Lactococcus lactis

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Release 2023.1 (January 2023)