BRENDA - Enzyme Database
show all sequences of 4.1.2.8

Arabidopsis indole synthase, a homolog of tryptophan synthase alpha, is an enzyme involved in the Trp-independent indole-containing metabolite biosynthesis

Zhang, R.; Wang, B.; Ouyang, J.; Li, J.; Wang, Y.; J. Integr. Plant Biol. 50, 1070-1077 (2008)

Data extracted from this reference:

Cloned(Commentary)
Cloned (Commentary)
Organism
CaMV35S-INS-GFP and CaMV35-TSA1-GFP are constructed, the INS open reading frame is subcloned into the vector pQE81
Arabidopsis thaliana
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Arabidopsis thaliana
5829
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate
Arabidopsis thaliana
-
indole + D-glyceraldehyde 3-phosphate
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Arabidopsis thaliana
O22765
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
cotyledon
-
Arabidopsis thaliana
-
flower
-
Arabidopsis thaliana
-
hypocotyl
-
Arabidopsis thaliana
-
root
-
Arabidopsis thaliana
-
rosette leaf
-
Arabidopsis thaliana
-
silique
-
Arabidopsis thaliana
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate
-
693498
Arabidopsis thaliana
indole + D-glyceraldehyde 3-phosphate
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
indole synthase
-
Arabidopsis thaliana
INS
-
Arabidopsis thaliana
tryptophan synthase alpha
-
Arabidopsis thaliana
Tsa1
-
Arabidopsis thaliana
Cloned(Commentary) (protein specific)
Commentary
Organism
CaMV35S-INS-GFP and CaMV35-TSA1-GFP are constructed, the INS open reading frame is subcloned into the vector pQE81
Arabidopsis thaliana
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Arabidopsis thaliana
5829
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate
Arabidopsis thaliana
-
indole + D-glyceraldehyde 3-phosphate
-
-
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
cotyledon
-
Arabidopsis thaliana
-
flower
-
Arabidopsis thaliana
-
hypocotyl
-
Arabidopsis thaliana
-
root
-
Arabidopsis thaliana
-
rosette leaf
-
Arabidopsis thaliana
-
silique
-
Arabidopsis thaliana
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate
-
693498
Arabidopsis thaliana
indole + D-glyceraldehyde 3-phosphate
-
-
-
?
Other publictions for EC 4.1.2.8
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
748938
Jin
Cloning and characterization ...
Persicaria tinctoria
Plant Cell Rep.
35
2449-2459
2016
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1
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1
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5
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1
1
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728444
Zhuang
Biosynthesis and emission of i ...
Oryza sativa
Phytochemistry
73
15-22
2012
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5
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728511
Ahmad
Benzoxazinoid metabolites regu ...
Zea mays
Plant Physiol.
157
317-327
2011
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1
1
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691511
Kriechbaumer
Characterisation of the trypto ...
Zea mays
BMC Plant Biol.
8
44
2008
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1
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5
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691784
Barends
Structure and mechanistic impl ...
Salmonella enterica subsp. enterica serovar Typhimurium
ChemBioChem
9
1024-1028
2008
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1
1
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691963
Barends
Tryptophan synthase, an allost ...
Salmonella enterica subsp. enterica serovar Typhimurium
Curr. Opin. Chem. Biol.
12
593-600
2008
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693498
Zhang
Arabidopsis indole synthase, a ...
Arabidopsis thaliana
J. Integr. Plant Biol.
50
1070-1077
2008
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1
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1
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1
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4
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6
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1
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4
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6
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695226
Dunn
Tryptophan synthase: the worki ...
Salmonella enterica subsp. enterica serovar Typhimurium
Trends Biochem. Sci.
33
254-264
2008
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2
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7
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1
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666055
Kulik
On the structural basis of the ...
Zea mays
J. Mol. Biol.
352
608-620
2005
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1
1
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670626
Farag
(Z)-3-Hexenol induces defense ...
Zea mays
Planta
220
900-909
2005
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670511
Frey
Transcriptional activation of ...
Zea mays
Phytochemistry
65
1047-1055
2004
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670717
Frey
An herbivore elicitor activate ...
Zea mays
Proc. Natl. Acad. Sci. USA
97
14801-14806
2000
1
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1
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4
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1
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670713
Melanson
A deletion in an indole syntha ...
Zea mays
Proc. Natl. Acad. Sci. USA
94
13345-13350
1997
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3
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670884
Frey
Analysis of a chemical plant d ...
Zea mays
Science
277
696-699
1997
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669170
Yanofsky
The enzymatic conversion of an ...
Escherichia coli
J. Biol. Chem.
223
171-184
1956
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