Protein Variants | Comment | Organism |
---|---|---|
R241C/A287V | the mutations dramatically increase the diastereoselectivity of the reverse aldol condensation activity for L-threo-3,4-dihydroxyphenylserine | Streptomyces coelicolor |
V86I/R241C/Y306C | the mutations dramatically increase the diastereoselectivity of the reverse aldol condensation activity for L-threo-3,4-dihydroxyphenylserine | Streptomyces coelicolor |
Y34C | the mutation dramatically increases the diastereoselectivity of the reverse aldol condensation activity for L-threo-3,4-dihydroxyphenylserine | Streptomyces coelicolor |
Y39C/Y306C | the mutations dramatically increase the diastereoselectivity of the reverse aldol condensation activity for L-threo-3,4-dihydroxyphenylserine | Streptomyces coelicolor |
Y39C/Y306C/A48T | the mutations dramatically increase the diastereoselectivity of the reverse aldol condensation activity for L-threo-3,4-dihydroxyphenylserine | Streptomyces coelicolor |
Y39C/Y306C/R316C | the mutations dramatically increase the diastereoselectivity of the reverse aldol condensation activity for L-threo-3,4-dihydroxyphenylserine | Streptomyces coelicolor |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Thr | Streptomyces coelicolor | - |
glycine + acetaldehyde | - |
? | |
L-Thr | Streptomyces coelicolor A3(2) | - |
glycine + acetaldehyde | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces coelicolor | - |
- |
- |
Streptomyces coelicolor A3(2) | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycine + 3,4-dihydroxybenzaldehyde | - |
Streptomyces coelicolor | L-threo-3,4-dihydroxyphenylserine + L-erythro-3,4-dihydroxyphenylserine | - |
r | |
glycine + 3,4-dihydroxybenzaldehyde | - |
Streptomyces coelicolor A3(2) | L-threo-3,4-dihydroxyphenylserine + L-erythro-3,4-dihydroxyphenylserine | - |
r | |
L-Thr | - |
Streptomyces coelicolor | glycine + acetaldehyde | - |
? | |
L-Thr | - |
Streptomyces coelicolor A3(2) | glycine + acetaldehyde | - |
? |
Synonyms | Comment | Organism |
---|---|---|
L-TA | - |
Streptomyces coelicolor |
L-threonine aldolase | - |
Streptomyces coelicolor |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Streptomyces coelicolor |