Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.1.2.4 extracted from

  • Rashid, N.; Imanaka, H.; Fukui, T.; Atomi, H.; Imanaka, T.
    Presence of a novel phosphopentomutase and a 2-deoxyribose 5-phosphate aldolase reveals a metabolic link between pentoses and central carbon metabolism in the hyperthermophilic archaeon Thermococcus kodakaraensis (2004), J. Bacteriol., 186, 4185-4191.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.2.4

Activating Compound

Activating Compound Comment Organism Structure
citrate enhances activity Thermococcus kodakarensis

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Thermococcus kodakarensis

Inhibitors

Inhibitors Comment Organism Structure
Zn2+ 1 mM, 35% decrease in activity Thermococcus kodakarensis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.81
-
 2-deoxy-D-ribose 5-phosphate 95°C Thermococcus kodakarensis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
24500
-
 2 * 24500, SDS-PAGE Thermococcus kodakarensis
53000
-
 gel filtration Thermococcus kodakarensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-deoxy-D-ribose 5-phosphate Thermococcus kodakarensis presence of a novel phosphopentomutase and a 2-deoxyribose 5-phosphate aldolase reveals a metabolic link between pentoses and central carbon metabolism. Alternative route for pentose biosynthesis trough the function of the novel phosphopentomutase and a 2-deoxyribose 5-phosphate aldolase D-glyceraldehyde 3-phosphate + acetaldehyde
-
 ?

Organism

Organism UniProt Comment Textmining
Thermococcus kodakarensis Q877I0 KOD1
-

Purification (Commentary)

Purification (Comment) Organism
-
 Thermococcus kodakarensis

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
285
-
 pH 4.0, 95°C Thermococcus kodakarensis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-deoxy-D-ribose 5-phosphate
-
 Thermococcus kodakarensis D-glyceraldehyde 3-phosphate + acetaldehyde
-
 ?
2-deoxy-D-ribose 5-phosphate presence of a novel phosphopentomutase and a 2-deoxyribose 5-phosphate aldolase reveals a metabolic link between pentoses and central carbon metabolism. Alternative route for pentose biosynthesis trough the function of the novel phosphopentomutase and a 2-deoxyribose 5-phosphate aldolase Thermococcus kodakarensis D-glyceraldehyde 3-phosphate + acetaldehyde
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 24500, SDS-PAGE Thermococcus kodakarensis

Synonyms

Synonyms Comment Organism
DERA
-
 Thermococcus kodakarensis
TK2104
-
 Thermococcus kodakarensis

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
95
-
-
 Thermococcus kodakarensis

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
85 100 85°C: about 35% of maximal activity, 100°C: about 95% of maximal activity Thermococcus kodakarensis

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
116
-
 2-deoxy-D-ribose 5-phosphate 95°C Thermococcus kodakarensis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4
-
-
 Thermococcus kodakarensis