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Literature summary for 4.1.2.27 extracted from
- Elevation of sphingoid base 1-phosphate as a potential contributor to hepatotoxicity in fumonisin B1-exposed mice (2007), Arch. Pharm. Res., 30, 962-969.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| fumonisin B1 | 10 mg/kg inhibits the expression of sphingosine 1-phosphate lyase | Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| sphingosine 1-phosphate | - |
Mus musculus | phosphoethanolamine + palmitaldehyde | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| sphingosine 1-phosphate lyase | - |
Mus musculus |
| SPL | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Mus musculus | |
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Release 2023.1 (January 2023)
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