Application | Comment | Organism |
---|---|---|
medicine | some effects of immune modulator FTY720 are due to disruption of sphingosine-1-phosphate metabolism | Mus musculus |
medicine | some effects of immune modulator FTY720 are due to disruption of sphingosine-1-phosphate metabolism | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
FTY720 | in vitro inhibition of enzyme, effects occurring from 300 nM concentrations on, maximal effects at 0.03 mM | Homo sapiens | |
FTY720 | in vivo enzyme inhibition concommitantly with lymphopenia, neither enzyme gene expression nor tissue enzyme protein expression is affected by inhibior | Mus musculus | |
FTY720 phosphate | less potent inhibitor than FTY720, effects only at 0.03 mM | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
expression in HEK293 cell | - |
Mus musculus | - |
female, 4 weeks old | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
thymus | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
SPL | - |
Mus musculus |
SPL | - |
Homo sapiens |