Any feedback?
Literature summary for 4.1.2.25 extracted from
- 6-Pyruvoyltetrahydropterin synthase paralogs replace the folate synthesis enzyme dihydroneopterin aldolase in diverse bacteria (2009), J. Bacteriol., 191, 4158-4165.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli folB deletant cells | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 7,8-dihydroneopterin | Escherichia coli | - |
6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde | - |
? |  |
| 7,8-dihydroneopterin | Escherichia coli MG1655 | - |
6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
| Escherichia coli MG1655 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 7,8-dihydroneopterin | - |
Escherichia coli | 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde | - |
? | |
| 7,8-dihydroneopterin | - |
Escherichia coli MG1655 | 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FolB | - |
Escherichia coli |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | 6-pyruvoyltetrahydropterin synthase paralogs with an active-site glutamate (designated PTPS-III proteins) can functionally replace FolB in vivo | Escherichia coli |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
