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Literature summary for 4.1.2.13 extracted from

  • Dawson, N.J.; Biggar, K.K.; Storey, K.B.
    Characterization of fructose-1,6-bisphosphate aldolase during anoxia in the tolerant turtle, Trachemys scripta elegans: an assessment of enzyme activity, expression and structure (2013), PLoS ONE, 8, e68830.
    View publication on PubMedView publication on EuropePMC
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KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00018
-
 D-fructose 1,6-bisphosphate pH 7.2, 25°C, anoxic liver preparation Trachemys scripta elegans
0.00024
-
 D-fructose 1,6-bisphosphate pH 7.2, 25°C, normoxic liver preparation Trachemys scripta elegans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
 4 * 37000, heterotetramer of isoforms A and B, SDS-PAGE Trachemys scripta elegans

Organism

Organism UniProt Comment Textmining
Trachemys scripta elegans
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Trachemys scripta elegans

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Trachemys scripta elegans
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
22.8
-
 pH 7.2, 25°C Trachemys scripta elegans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-fructose 1,6-bisphosphate
-
 Trachemys scripta elegans dihydroxyacetone phosphate + glyceraldehyde-3-phosphate
-
 ?
additional information enzyme favors D-fructose-1,6-bisphosphate as a substrate over D-fructose-1-phosphate and is unchanged between normoxia and anoxia Trachemys scripta elegans ?
-
 ?

Subunits

Subunits Comment Organism
heterotetramer 4 * 37000, heterotetramer of isoforms A and B, SDS-PAGE Trachemys scripta elegans

Expression

Organism Comment Expression
Trachemys scripta elegans expression level of both isoforms A and B increases in liver tissue to 1.6fold after 20 h anoxia, without significant change in the ratio of isoforms up