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Literature summary for 4.1.2.11 extracted from

  • Gruber, K.; Kratky, C.
    Biopolymers for biocatalysis: Structure and catalytic mechanism of hydroxynitrile lyases (2004), J. Polym. Sci. A, 42, 479-486.
No PubMed abstract available
Search for more literature for 4.1.2.11

Application

Application Comment Organism
synthesis first (S)-HNL used in organic solvents for the preparation of (S)-cyanohydrins Sorghum bicolor

Cloned(Commentary)

Cloned (Comment) Organism
-
 Sorghum bicolor

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Sorghum bicolor

Inhibitors

Inhibitors Comment Organism Structure
benzoic acid
-
 Sorghum bicolor

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cyanide + 4-hydroxybenzaldehyde Sorghum bicolor
-
 (S)-p-hydroxymandelonitrile
-
 ?

Organism

Organism UniProt Comment Textmining
Sorghum bicolor P52708
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyanide + 4-hydroxybenzaldehyde
-
 Sorghum bicolor (S)-p-hydroxymandelonitrile
-
 ?
HCN + 4-hydroxybenzaldehyde (S)-specific Sorghum bicolor (S)-4-hydroxymandelonitrile
-
 ?
additional information substrate range of SbHNL is limited to aromatic and heteroaromatic aldehydes, does not accept aliphatic aldehydes as substrates Sorghum bicolor ?
-
 ?

Subunits

Subunits Comment Organism
heterotetramer alpha2,beta2 heterotetramer consisting of two alpha,beta heterodimers Sorghum bicolor

Synonyms

Synonyms Comment Organism
HNL
-
 Sorghum bicolor
Hydroxynitrile lyase
-
 Sorghum bicolor
SbHNL
-
 Sorghum bicolor