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Literature summary for 4.1.1.96 extracted from

  • Hanfrey, C.C.; Pearson, B.M.; Hazeldine, S.; Lee, J.; Gaskin, D.J.; Woster, P.M.; Phillips, M.A.; Michael, A.J.
    Alternative spermidine biosynthetic route is critical for growth of Campylobacter jejuni and is the dominant polyamine pathway in human gut microbiota (2011), J. Biol. Chem., 286, 43301-43312.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Campylobacter jejuni the Campylobacter jejuni enzyme is a carboxyspermidine decarboxylase and not a carboxynorspermidine decarboxylase in vivo and is essential for spermidine biosynthesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni
-
 NCTC11828
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
carboxynorspermidine the enzyme has relatively equal preference for carboxynorspermidine and carboxyspermidine Campylobacter jejuni bis(3-aminopropyl)amine + CO2
-
 ?
carboxyspermidine the enzyme has relatively equal preference for carboxynorspermidine and carboxyspermidine Campylobacter jejuni spermidine + CO2
-
 ?
additional information the Campylobacter jejuni enzyme is a carboxyspermidine decarboxylase and not a carboxynorspermidine decarboxylase in vivo and is essential for spermidine biosynthesis Campylobacter jejuni ?
-
 ?

Synonyms

Synonyms Comment Organism
CANSDC
-
 Campylobacter jejuni

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Campylobacter jejuni