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Literature summary for 4.1.1.90 extracted from
- gamma-Glutamyl carboxylase in osteoblasts regulates glucose metabolism in mice (2014), Biochem. Biophys. Res. Commun., 453, 350-355 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q3TME3 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| osteoblast | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GGCX | - |
Mus musculus |
| vitamin K-dependent gamma-glutamyl carboxylase | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | GGCX expressed in osteoblasts is critical for the maintenance of blood glucose and white adipose tissue. Osteoblast-specific conditional Ggcx-deficient mice exhibit altered metabolism compared with their controls. Serum glucose levels can be maintained with low amounts of insulin, and the weight of white adipose tissue significantly decreases | Mus musculus |
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Release 2023.1 (January 2023)
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