Literature summary for 4.1.1.90 extracted from

Wu, S.; Liu, S.; Davis, C.H.; Stafford, D.W.; Kulman, J.D.; Pedersen, L.G.
A hetero-dimer model for concerted action of vitamin K carboxylase and vitamin K reductase in vitamin K cycle (2011), J. Theor. Biol., 279, 143-149.

Search for more literature for 4.1.1.90

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum membrane	-	Homo sapiens	5789	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	A7YA96	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-glutamate + CO2 + O2 + vitamin K hydroquinone	-	Homo sapiens	gamma-carboxy L-glutamate + vitamin K epoxide + H2O	-	ir

Subunits

Subunits	Comment	Organism
heterodimer	-	Homo sapiens

Synonyms

Synonyms	Comment	Organism
GGCX	-	Homo sapiens
vitamin K carboxylase	-	Homo sapiens
VKC	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
vitamin K	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	VKC maintains vitamin K levels and sustains the blood coagulation cascade	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)