Literature summary for 4.1.1.90 extracted from

Li, Q.; Uitto, J.
The mineralization phenotype in Abcc6 (-/-) mice is affected by Ggcx gene deficiency and genetic background--a model for pseudoxanthoma elasticum (2010), J. Mol. Med., 88, 173-181.

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Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Synonyms

Synonyms	Comment	Organism
gamma-glutamyl carboxylase	-	Mus musculus
GGCX	-	Mus musculus

General Information

General Information	Comment	Organism
malfunction	onset of mineralization in Abcc6-/-, Ggcx+/+ mice is delayed until between 3 and 4 months of age, suggesting that the genetic background plays a role in modifying the mineralization process. Mineralization in the Abcc6-/-, Ggcx+/- mice is accelerated in comparison with age-matched Abcc6-/-, Ggcx+/+ mice, with ca. 3fold difference at 3, 4, and 9 months of age	Mus musculus

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Release 2023.1 (January 2023)