Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | vitamin K-dependent carboxylation of glutamate to form gamma-carboxyglutamate (Gla) is unusual among known posttranslational modifications in that substrate recognition does not require a specific sequence around the glutamate residues to be modified | ? | - |
? | |
additional information | Bos taurus | vitamin K-dependent carboxylation of glutamate to form gamma-carboxyglutamate (Gla) is unusual among known posttranslational modifications in that substrate recognition does not require a specific sequence around the glutamate residues to be modified | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | Q07175 | - |
- |
Homo sapiens | P38435 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate + CO2 + O2 + vitamin K hydroquinone | - |
Homo sapiens | gamma-carboxy L-glutamate + vitamin K epoxide + H2O | - |
? | |
L-glutamate + CO2 + O2 + vitamin K hydroquinone | - |
Bos taurus | gamma-carboxy L-glutamate + vitamin K epoxide + H2O | - |
? | |
additional information | vitamin K-dependent carboxylation of glutamate to form gamma-carboxyglutamate (Gla) is unusual among known posttranslational modifications in that substrate recognition does not require a specific sequence around the glutamate residues to be modified | Homo sapiens | ? | - |
? | |
additional information | vitamin K-dependent carboxylation of glutamate to form gamma-carboxyglutamate (Gla) is unusual among known posttranslational modifications in that substrate recognition does not require a specific sequence around the glutamate residues to be modified | Bos taurus | ? | - |
? | |
additional information | identification of a striking homology between exon 3 in all known matrix Gla proteins and a 24-residue sequence in the bovine and human gamma-glutamyl carboxylases. Alignment of exon 3 of matrix Gla protein with the homologous region of the gamma-glutamyl carboxylase shown | Homo sapiens | ? | - |
? | |
additional information | identification of a striking homology between exon 3 in all known matrix Gla proteins and a 24-residue sequence in the bovine and human gamma-glutamyl carboxylases. Alignment of exon 3 of matrix Gla protein with the homologous region of the gamma-glutamyl carboxylase shown | Bos taurus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
gamma-glutamyl carboxylase | - |
Homo sapiens |
gamma-glutamyl carboxylase | - |
Bos taurus |
glutamate carboxylase | - |
Homo sapiens |
glutamate carboxylase | - |
Bos taurus |
matrix gamma-carboxyglutamate protein | - |
Homo sapiens |
matrix gamma-carboxyglutamate protein | - |
Bos taurus |
matrix Gla protein | - |
Homo sapiens |
matrix Gla protein | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
vitamin K | - |
Homo sapiens | |
vitamin K | - |
Bos taurus |