Inhibitors | Comment | Organism | Structure |
---|---|---|---|
iodoacetic acid | poor inhibitor | Rattus norvegicus | |
N-ethylmaleimide | preincubation with vitamin K hydroquinone prevents NEM inhibition of epoxide formation but not of carboxylation | Rattus norvegicus | |
p-hydroxymercuribenzoate | 1 mM, more than 90% inhibition, inhibition is reversed by dithiothreitol | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | O88496 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | separate active sites are required to support vitamin K-dependent epoxide formation and carboxylation. The binding site for vitamin K oxygenase contains an active thiol group | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glutamate carboxylase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
vitamin K | - |
Rattus norvegicus |