Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CBM-3001106 | - |
Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Malonyl-CoA | Mus musculus | - |
Acetyl-CoA + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q99J39 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Malonyl-CoA | - |
Mus musculus | Acetyl-CoA + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
malonyl CoA decarboxylase | - |
Mus musculus |
MCD | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | decreased fat oxidation in enzyme-deficient mice results in the accumulation of lipid intermediates in peripheral tissues, but this is not associated with a worsening of age-associated insulin resistance and, conversely, improves longevity. This improvement is associated with reduced oxidative stress and reduced acetylation of the antioxidant enzyme superoxide dismutase 2 in muscle but not the liver | Mus musculus |