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Literature summary for 4.1.1.9 extracted from

  • Hwang, I.W.; Makishima, Y.; Suzuki, T.; Kato, T.; Park, S.; Terzic, A.; Chung, S.K.; Park, E.Y.
    Phosphorylation of Ser-204 and Tyr-405 in human malonyl-CoA decarboxylase expressed in silkworm Bombyx mori regulates catalytic decarboxylase activity (2015), Appl. Microbiol. Biotechnol., 99, 8977-8986 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Bombyx mori Homo sapiens

Protein Variants

Protein Variants Comment Organism
S204G the mutant shows 51% of wild type activity Homo sapiens
Y405F the mutant shows about 56-64% of wild type activity Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Malonyl-CoA Homo sapiens
-
Acetyl-CoA + CO2
-
ir

Organism

Organism UniProt Comment Textmining
Homo sapiens O95822
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein phosphorylated at Ser-204 and Tyr-405 Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
anti-FLAG M2 affinity gel column chromatography Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Malonyl-CoA
-
Homo sapiens Acetyl-CoA + CO2
-
ir

Subunits

Subunits Comment Organism
? x * 50000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
MCD
-
Homo sapiens