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Literature summary for 4.1.1.9 extracted from

  • Mulder, H.; Lu, D.; Finley IV, J.; An, J.; Cohen, J.; Antinozzi, P.A.; McGarry, J.D.; Newgard, C.B.
    Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells (2001), J. Biol. Chem., 276, 6479-6484.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
overexpression of MCD lacking both its mitochondrial and peroxisomal targeting sequences in INS-1-derived 832/13 beta-cells, effect of MCD expression on glucose-stimulated insulin secretion Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol recombinant MCD lacking its mitochondrial and peroxisomal targeting sequences Homo sapiens 5829
-
additional information MCD contains mitochondrial and peroxisomal targeting sequences Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Malonyl-CoA Homo sapiens
-
Acetyl-CoA + CO2
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Malonyl-CoA
-
Homo sapiens Acetyl-CoA + CO2
-
?