Protein Variants | Comment | Organism |
---|---|---|
G462A | mutation in the conserved LGST motif, mutant retains some, albeit reduced, phosphatidylserine decarboxylase activity | Saccharomyces cerevisiae |
L461A | mutation in the conserved LGST motif, mutant retains some, albeit reduced, phosphatidylserine decarboxylase activity | Saccharomyces cerevisiae |
S463A | mutation of the conserved serine residue, completely abolishes decarboxylase activity | Saccharomyces cerevisiae |
T464I | mutation in the conserved LGST motif, mutant retains some, albeit reduced, phosphatidylserine decarboxylase activity | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | autocatalytic processing in the mitochondrion | Saccharomyces cerevisiae | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | P39006 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | a conserved LGST motif separates the enzyme into alpha- and beta-subunits. Only the serine residue of the motif is absolutely required for Psd1 autocatalysis and function. Yeast Psd1 does not require its substrate phosphatidylserine for autocatalysis. Yeast Psd1 autocatalysis does not require mitochondrion-specific phospholipids, proteins, or cofactors | Saccharomyces cerevisiae |
Synonyms | Comment | Organism |
---|---|---|
PSD1 | - |
Saccharomyces cerevisiae |