KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.11 | - |
S-adenosyl-L-methionine | enzyme in complex with prozyme, absence of putrescine, 37°C, pH 8.0 | Trypanosoma brucei | |
0.17 | - |
S-adenosyl-L-methionine | enzyme in complex with prozyme, presence of putrescine, 37°C, pH 8.0 | Trypanosoma brucei | |
0.24 | - |
S-adenosyl-L-methionine | free enzyme, presence of putrescine, 37°C, pH 8.0 | Trypanosoma brucei | |
0.38 | - |
S-adenosyl-L-methionine | free enzyme, absence of putrescine, 37°C, pH 8.0 | Trypanosoma brucei |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei | A5HNV7 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine | - |
Trypanosoma brucei | (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | Trypanosoma brucei contains both a functional enzyme and a prozyme that has lost catalytic activity. The prozyme forms a high-affinity heterodimer with the enzyme that stimulates its activity up to 1200fold, the heterodimer is the functional enzyme in vivo | Trypanosoma brucei |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0013 | - |
S-adenosyl-L-methionine | free enzyme, absence of putrescine, 37°C, pH 8.0 | Trypanosoma brucei | |
0.0082 | - |
S-adenosyl-L-methionine | free enzyme, presence of putrescine, 37°C, pH 8.0 | Trypanosoma brucei | |
1.4 | - |
S-adenosyl-L-methionine | enzyme in complex with prozyme, absence of putrescine, 37°C, pH 8.0 | Trypanosoma brucei | |
1.7 | - |
S-adenosyl-L-methionine | enzyme in complex with prozyme, presence of putrescine, 37°C, pH 8.0 | Trypanosoma brucei |