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Literature summary for 4.1.1.50 extracted from
- Thymosin beta4 is a determinant of the transformed phenotype and invasiveness of S-adenosylmethionine decarboxylase-transfected fibroblasts (2006), Cancer Res., 66, 701-712.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in sense and antisense orientations in mouse NIH3T3 cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | S-adenosylmethionine decarboxylase is a key enzyme in the synthesis of polyamines essential for cell growth and proliferation. Its overexpression induces the transformation of murine fibroblasts in both sense and antisense orientations, yielding highly invasive tumors in nude mice. Thymosin B4 is a determinant of the transformed phenotype and invasiveness of S-adenosylmethionine decarboxylasetransfected fibroblasts | Homo sapiens | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AdoMetDC | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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