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Literature summary for 4.1.1.50 extracted from

  • Markham, G.D.; Tabor, C.W.; Tabor, H.
    S-Adenosylmethionine decarboxylase (Escherichia coli) (1983), Methods Enzymol., 94, 228-230.
    View publication on PubMed
Search for more literature for 4.1.1.50

Activating Compound

Activating Compound Comment Organism Structure
pyruvate each subunit contains one covalently linked pyruvate Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt competitive with respect to S-adenosylmethionine Escherichia coli
methylglyoxal bis(guanylhydrazone)
-
 Escherichia coli
NaCNBH3 inactivation in presence of adenosylmethionine and Mg2+, no inactivation in absence of substrate and Mg2+ Escherichia coli
phenylhydrazine
-
 Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ requires a divalent cation, Mg2+, Ca2+ or Mn2+ Escherichia coli
Mg2+ requires a divalent cation, Mg2+, Ca2+ or Mn2+ Escherichia coli
Mn2+ requires a divalent cation, Mg2+, Ca2+ or Mn2+ Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
17000
-
 6 * 17000 Escherichia coli
108000
-
-
 Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.88
-
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine
-
 Escherichia coli (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
 ?

Subunits

Subunits Comment Organism
hexamer 6 * 17000 Escherichia coli