Literature summary for 4.1.1.49 extracted from

Furukawa, F.; Tseng, Y.C.; Liu, S.T.; Chou, Y.L.; Lin, C.C.; Sung, P.H.; Uchida, K.; Lin, L.Y.; Hwang, P.P.
Induction of phosphoenolpyruvate carboxykinase (PEPCK) during acute acidosis and its role in acid secretion by V-ATPase-expressing ionocytes (2015), Int. J. Biol. Sci., 11, 712-725 .

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Organism

Organism	UniProt	Comment	Textmining
Danio rerio	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
larva	-	Danio rerio	-

Expression

Organism	Comment	Expression
Danio rerio	expression increases in response to acid stress	up

General Information

General Information	Comment	Organism
physiological function	Danio rerio larvae show increased V-ATPase-mediated acid secretion and transient expression of Pck1, in response to acid stress. Pck1 gene knockdown decreases the H+ secretion via V-ATPase, the effect is rescued by supplementation of glucose into the yolk. Pck1 knockdown does not affect glutamine/glutamate catalysis	Danio rerio

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Release 2023.1 (January 2023)