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Literature summary for 4.1.1.49 extracted from
- Stereochemistry of the carboxylation reaction catalyzed by the ATP-dependent phosphoenolpyruvate carboxykinases from Saccharomyces cerevisiae and Anaerobiospirillum succiniciproducens (2008), Biochimie, 90, 1685-1692.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0059 | - |
(Z)-3-fluorophosphoenolpyruvate | - |
Anaerobiospirillum succiniciproducens |  |
| 0.0085 | - |
(Z)-3-fluorophosphoenolpyruvate | - |
Saccharomyces cerevisiae | |
| 0.083 | - |
phosphoenolpyruvate | - |
Anaerobiospirillum succiniciproducens | |
| 0.402 | - |
phosphoenolpyruvate | - |
Saccharomyces cerevisiae | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Anaerobiospirillum succiniciproducens | O09460 | - |
- |
| Saccharomyces cerevisiae | P10963 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + (E)-3-fluorophosphoenolpyruvate + CO2 | - |
Saccharomyces cerevisiae | ATP + 3-fluorooxaloacetate | - |
? | |
| ADP + (E)-3-fluorophosphoenolpyruvate + CO2 | - |
Anaerobiospirillum succiniciproducens | ATP + 3-fluorooxaloacetate | - |
? | |
| ADP + (Z)-3-fluorophosphoenolpyruvate + CO2 | - |
Saccharomyces cerevisiae | ATP + 3-fluorooxaloacetate | - |
? | |
| ADP + (Z)-3-fluorophosphoenolpyruvate + CO2 | - |
Anaerobiospirillum succiniciproducens | ATP + 3-fluorooxaloacetate | - |
? | |
| ADP + phosphoenolpyruvate + CO2 | - |
Saccharomyces cerevisiae | ATP + oxaloacetate | - |
? | |
| ADP + phosphoenolpyruvate + CO2 | - |
Anaerobiospirillum succiniciproducens | ATP + oxaloacetate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PEP carboxykinase | - |
Saccharomyces cerevisiae |
| PEP carboxykinase | - |
Anaerobiospirillum succiniciproducens |
| phosphoenolpyruvate carboxykinase | - |
Saccharomyces cerevisiae |
| phosphoenolpyruvate carboxykinase | - |
Anaerobiospirillum succiniciproducens |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.33 | - |
(Z)-3-fluorophosphoenolpyruvate | - |
Anaerobiospirillum succiniciproducens | |
| 1.1 | - |
(Z)-3-fluorophosphoenolpyruvate | - |
Saccharomyces cerevisiae | |
| 22 | - |
phosphoenolpyruvate | - |
Anaerobiospirillum succiniciproducens | |
| 53 | - |
phosphoenolpyruvate | - |
Saccharomyces cerevisiae | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Saccharomyces cerevisiae | |
| ATP | - |
Anaerobiospirillum succiniciproducens | |
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Release 2023.1 (January 2023)
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