Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis(2-nitrobenzoate) | - |
Trypanosoma cruzi | |
Fluorescein mercuric acetate | - |
Trypanosoma cruzi | |
IDP | inhibits exchange reaction with ATP or GTP | Trypanosoma cruzi | |
o-Iodosobenzoate | 0.5 mM, 50% inhibition | Trypanosoma cruzi | |
p-chloromercuribenzenesulfonate | - |
Trypanosoma cruzi | |
p-chloromercuribenzoate | - |
Trypanosoma cruzi |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.017 | - |
ADP | ADP in form of MnADP- | Trypanosoma cruzi | |
0.019 | - |
ATP | exchange reaction | Trypanosoma cruzi | |
0.019 | - |
ATP | ATP in form of MnATP2- | Trypanosoma cruzi | |
0.027 | - |
ATP | ATP in form of MnATP2- | Trypanosoma cruzi | |
0.035 | - |
phosphoenolpyruvate | - |
Trypanosoma cruzi | |
0.041 | - |
oxaloacetate | exchange reaction | Trypanosoma cruzi | |
0.044 | - |
oxaloacetate | - |
Trypanosoma cruzi |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | exchange reaction: Mn2+ is the most effective divalent cation activator followed by Cd2+ and Mg2+ | Trypanosoma cruzi | |
Mg2+ | exchange reaction: MnCl2 is the most effective divalent cation activator followed by Cd2+ and Mg2+ | Trypanosoma cruzi | |
Mn2+ | exchange reaction: Mn2+ is the most effective divalent cation activator followed by Cd2+ and Mg2+ | Trypanosoma cruzi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma cruzi | - |
Tul O strain | - |
Trypanosoma cruzi Tul O | - |
Tul O strain | - |
Purification (Comment) | Organism |
---|---|
- |
Trypanosoma cruzi |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epimastigote | - |
Trypanosoma cruzi | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Trypanosoma cruzi |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + phosphoenolpyruvate + CO2 | - |
Trypanosoma cruzi | ATP + oxaloacetate | - |
? | |
ADP + phosphoenolpyruvate + CO2 | - |
Trypanosoma cruzi Tul O | ATP + oxaloacetate | - |
? | |
ATP + oxaloacetate | - |
Trypanosoma cruzi | ADP + phosphoenolpyruvate + CO2 | - |
? | |
ATP + oxaloacetate | - |
Trypanosoma cruzi Tul O | ADP + phosphoenolpyruvate + CO2 | - |
? | |
CTP + oxaloacetate | 15% of the activity with ATP | Trypanosoma cruzi | CDP + phosphoenolpyruvate + CO2 | - |
? | |
GTP + oxaloacetate | 52% of the activity with ATP | Trypanosoma cruzi | GDP + phosphoenolpyruvate + CO2 | - |
? | |
GTP + oxaloacetate | 52% of the activity with ATP | Trypanosoma cruzi Tul O | GDP + phosphoenolpyruvate + CO2 | - |
? | |
ITP + oxaloacetate | 36% of the activity with ATP | Trypanosoma cruzi | IDP + phosphoenolpyruvate + CO2 | - |
? | |
ITP + oxaloacetate | 36% of the activity with ATP | Trypanosoma cruzi Tul O | IDP + phosphoenolpyruvate + CO2 | - |
? | |
additional information | CO2-exchange reaction with ATP, GTP, ITP, CTP, UTP and TTP | Trypanosoma cruzi | ? | - |
? | |
additional information | CO2-exchange reaction with ATP, GTP, ITP, CTP, UTP and TTP | Trypanosoma cruzi Tul O | ? | - |
? | |
TTP + oxaloacetate | 16% of the activity with ATP | Trypanosoma cruzi | TDP + phosphoenolpyruvate + CO2 | - |
? | |
UTP + oxaloacetate | 20% of the activity with ATP | Trypanosoma cruzi | UDP + phosphoenolpyruvate + CO2 | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.5 | - |
o-Iodosobenzoate | - |
Trypanosoma cruzi |