Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharolobus solfataricus | Q06121 | - |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O | molecular dynamics study at different temperatures. K110 is the general acid, E210 the general base. At higher temperature, the enzyme-substrate electrostatic interaction favors the binding of the substrate in near attack conformation, at lower temperature, the substrate is bound in nonreactive conformation | Saccharolobus solfataricus |