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Literature summary for 4.1.1.48 extracted from
- Purification and comparison of the N-(5'-phosphoribosyl)anthranilic acid isomerase/indole-3-glycerol phosphate synthetase of tryptophan biosynthesis from three species of Enterobacteriaceae (1970), Eur. J. Biochem., 16, 199-207.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 44000 | - |
equilibrium sedimentation | Klebsiella aerogenes |
| 45000 | - |
1 * 45000, SDS-PAGE | Salmonella enterica subsp. enterica serovar Typhimurium |
| 45000 | - |
1 * 45000, SDS-PAGE | Escherichia coli |
| 45000 | - |
1 * 45000, SDS-PAGE | Klebsiella aerogenes |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
bifunctional enzyme phosphoribosylanthranilate isomerase-indoleglycerol phosphate synthetase, Ec4.1.1.48/Ec5.3.1.24 | - |
| Klebsiella aerogenes | - |
- |
- |
| Salmonella enterica subsp. enterica serovar Typhimurium | - |
bifunctional enzyme phosphoribosylanthranilate isomerase-indoleglycerol phosphate synthetase, Ec4.1.1.48/Ec5.3.1.24 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
- |
Klebsiella aerogenes |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 2.3 | - |
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
| 3.2 | - |
- |
Klebsiella aerogenes |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | 1-(3-Indolyl)glycerol-3-phosphate + CO2 + H2O | - |
? |  |
| 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate | - |
Escherichia coli | 1-(3-Indolyl)glycerol-3-phosphate + CO2 + H2O | - |
? | |
| 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate | - |
Klebsiella aerogenes | 1-(3-Indolyl)glycerol-3-phosphate + CO2 + H2O | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 45000, SDS-PAGE | Salmonella enterica subsp. enterica serovar Typhimurium |
| monomer | 1 * 45000, SDS-PAGE | Escherichia coli |
| monomer | 1 * 45000, SDS-PAGE | Klebsiella aerogenes |
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